Do you remember Quark XPress? It was once the leading application for professional desktop publishing, and many big names in magazine and newspaper publishing used Quark throughout their offices.
Then Adobe was able to advance with InDesign as a direct competition. Adobe's tactic to combine InDesign with the Illustrator/Photoshop suite made it a serious competitor which gained more and more followers (not me by the way). Quark lagged behind due to their bad upgrade and support policy and almost disappeared. Since a few years, they have re-invented themselves, and Quark has been regularly updated and affordably priced. Disappointed Adobe users begin to return.
Quark's strongest point is a multi-platform approach. Print, web and now tablet as well as mobile can be designed and transformed easily. Flash and interactive content are highly integrated.
For me, Quark and FreeHand always felt alike. The same intuitive spirit it seems.
Could Quark be(come) interested in FreeHand? Their newest vesion 9 has some design features, but FH would be way ahead.